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简纪常，二级教授，博士，博士生导师，现任研究生院院长。教育部高等学校水产类专业教学指导委员会委员，广东省水产经济动物病原生物学及流行病学重点实验室和水产经济动物病害广东省高等学校重点实验室副主任。曾被评为湛江市“十大”优秀青年、广东省教工委优秀共产党员和湛江市五一劳动奖章。入选广东省普通高等学校“千百十工程”省级培养对象、广东省扬帆计划高层次人才。中国水产学会理事、中国水产学会鱼病专业委员会委员，中国微生物学会海洋微生物学分会理事、国际鱼类免疫学会员、广东省海洋与湖沼学会和中国海洋学会热带海洋分会常务理事、湛江市水产动物疾病防治学会召集人。领导的... 详细>>

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共 315 条记录，以下是 1-30

Effects of traditional Chinese medicine on nonspecific immunity and disease resistance of large yellow croaker, Pseudosciaena crocea (Richardson): AQUACULTUREJian J. Wu Z. 出版年：2003; The influence of traditional Chinese medicine (TCM) formulated from Astragalus Root (Radix astragalin seu Hedysari) and Chinese Angelica Root (Radix angelicae sinensis) at the rate of 5:1 (w/w) on nonspecific immunity in...

中草药对建鲤非特异性免疫功能的影响: 《大连水产学院学报》简纪常吴灶和出版年：2002; 用添加中草药的鲤配合饲料饲喂建鲤(Cyprinnus var．Jian)后,测定了建鲤非特异性免疫指标。饲喂药饵Ⅰ 10、15、30 d后,氯化硝基四氮唑兰(NBT)阳性细胞数分别为 27±3．45、39±6．04和 3...; 关键词：非特异性免疫功能建鲤中草药 NBT阳性细胞溶菌酶免疫增强剂饲料添加剂 被引量：133

Effects of a commercial probiotic BS containing Bacillus subtilis and Bacillus licheniformis on growth, immune response and disease resistance in Nile tilapia, Oreochromis niloticus: FISH & SHELLFISH IMMUNOLOGYAbarike, Emmanuel Delwin Cai, Jia Lu, Yishan Yu, Huang Chen, Lihua Jian, Jichang Tang, Jufen Jun, Liang Kuebutornye, Felix K. A. 出版年：2018; The present study evaluated a commercial probiotic designated as BS (a mix of B. subtilis and B. licheniformis) to ascertain its efficacy and the dose necessary to improve growth, immune response, and disease resistance ...

Cloning and expression of heat shock protein 70 gene in the haemocytes of pearl oyster (Pinctada fucata, Gould 1850) responding to bacterial challenge: FISH & SHELLFISH IMMUNOLOGYWang, Zhongliang Wu, Zaohe Jian, Jichang Lu, Yishan 出版年：2009; The cdNA of pearl oyster Pinctada fucata Hsp70 (designated PFHsp70) was cloned by EST and rapid amplification of cdNA ends (RACE) techniques. The full length of PFHsp70 cdNA was 2376 bp, consisting of a 5'-terminal untra...

Comprehensive identification and profiling of Nile tilapia (Oreochromis niloticus) microRNAs response to Streptococcus agalactiae infection through high-throughput sequencing: FISH & SHELLFISH IMMUNOLOGYWang, Bei Gan, Zhen Cai, Shuanghu Wang, Zhongliang Yu, Dapeng Lin, Ziwei Lu, Yishan Wu, Zaohe Jian, Jichang 出版年：2016; MicroRNAs are a kind of small non-coding RNAs that participate in various biological processes. Deregulated microRNA expression is associated with several types of diseases. Tilapia (Oreochromis niloticus) is an importan...

Immunostimulatory effects of artificial feed supplemented with a Chinese herbal mixture on Oreochromis niloticus against Aeromonas hydrophila: FISH & SHELLFISH IMMUNOLOGYTang, Jufen Cai, Jia Liu, Ran Wang, Jiamin Lu, Yishan Wu, Zaohe Jian, Jichang 出版年：2014; The effects of a Chinese herbal mixture (CHM) composed of astragalus, angelica, hawthorn, Licorice root and honeysuckle on immune responses and disease resistant of Nile tilapia (Oreochromis niloticus GIFT strain) were i...

恩诺沙星在眼斑拟石首鱼体内的药物代谢动力学: 《中国兽医学报》简纪常吴灶和陈刚出版年：2005; 应用反相高效液相色谱法 (RP- HPL C)研究了恩诺沙星在眼斑拟石首鱼 (Sciaenops ocellatus)体内的药物代谢动力学。实验数据经 DAS药代动力学分析软件分析后得出 :腹腔注射组血浆的药时数据符合一...; 关键词：眼斑拟石首鱼恩诺沙星药物代谢动力学反相高效液相色谱法 被引量：45

Influence of traditional Chinese medicine and Bacillus species (TCMBS) on growth, immune response and disease resistance in Nile tilapia, Oreochromis niloticus: AQUACULTURE RESEARCHAbarike, Emmanuel Delwin Jian, Jichang Tang, Jufen Cai, Jia Yu, Huang Chen Lihua Jun, Liang 出版年：2018; Multispecies herbs and probiotic bacteria offered to fish might enhance their immune response and increase disease resistance, but the dose effects of herbal-probiotic application remain unclear. Therefore, the effect of...

利用有益微生物改善养殖生态环境的研究: 《湛江海洋大学学报》陈家长简纪常胡庚东吴伟瞿建宏出版年：2002; 研究了噬菌蛭弧菌在实验室条件下对水产养殖中常见病菌的裂解能力及噬菌蛭弧菌和光合细菌对池塘生态环境的改善作用。结果表明 ,噬菌蛭菌对嗜水气单胞菌具有裂解作用 ,噬菌蛭弧菌和光合细菌结合使用对养殖环境具有明显的改善作用。 2...; 关键词：有益微生物养殖生态环境噬菌蛭弧菌光合细菌嗜水气单胞菌 被引量：38

Construction of a Vibrio alginolyticus hopPmaJ (hop) mutant and evaluation of its potential as a live attenuated vaccine in orange-spotted grouper (Epinephelus coioides): FISH & SHELLFISH IMMUNOLOGYPang, Huanying Qiu, Mingsheng Zhao, Jingmin Hoare, Rowena Monaghan, Sean J. Song, Dawei Chang, Yunsheng Jian, Jichang 出版年：2018; Vibrio alginolyticus, a bacterial pathogen in fish and humans, expresses a type III secretion system (T3SS) that is critical for pathogen virulence and disease development. However, little is known about the associated e...

海水网箱养殖军曹鱼弧菌病病原的分离及其特性: 《中国兽医学报》简纪常吴灶和陈刚曾敏玲出版年：2003; 从海水网箱养殖的患病军曹鱼 (Rachycentron canadum)的肾脏、肝脏等实质器官及腹水中分离出 1株致病菌即JA- 4 6菌。其特点如下 :革兰氏阴性短杆菌 ,极端单鞭毛 ,大小为 (1～ 2 )μm× (...; 关键词：军曹鱼海水网箱养殖弧菌病创伤弧菌药敏试验生物学特性 被引量：33

NK-lysin from Oreochromis niloticus improves antimicrobial defence against bacterial pathogens: FISH & SHELLFISH IMMUNOLOGYHuang, Yu Zheng, Qi Niu, Jinzhong Tang, Jufen Wang, Bei Abarike, Emmanuel Delwin Lu, Yishan Cai, Jia Jian, Jichang 出版年：2018; NK-lysin, an effector of cytotoxic T cells and natural killer cells, is a potent antimicrobial peptide widely distributed in mammals. Homologues of NK-lysin have been discovered in several teleost species, but only sever...

Conservation of structural and interactional features of cd28 and cd80/86 molecules from Nile tilapia (Oreochromis niloticus): FISH & SHELLFISH IMMUNOLOGYHuang, Yu Wang, Zhiwen Zheng, Qi Tang, Jufen Cai, Jia Lu, Yishan Jian, Jichang 出版年：2018; Interaction of cd28 with cd80 or cd86 molecules provides a costimulatory signals required in T cell activation. In this study, we cloned and analyzed a cd28 gene (On-cd28) and a cd80/86 gene (On-cd80/86) from Nile tilapi...

溶藻弧菌脂多糖对石斑鱼免疫功能的影响: 《水生生物学报》简纪常叶剑敏吴灶和出版年：2004; 关键词：石斑鱼溶藻弧菌脂多糖免疫功能 被引量：29

卵形鲳鲹结节病病原的分离与鉴定: 《广东海洋大学学报》黄郁葱简纪常吴灶和鲁义善余坦健出版年：2008; 从湛江港、阳江闸坡海水网箱养殖的患结节病卵形鲳鲹(Trachinotus ovatus)中分离一株细菌,回归感染结果证明该菌是引起卵形鲳鲹结节病的病原,对卵形鲳鲹半致死浓度为45 g-1。该菌株呈革兰阳性,好氧,具有弱抗...; 关键词：卵形鲳鲹结节病诺卡氏菌 16S rDNA 被引量：29

VscO, a putative T3SS chaperone escort of Vibrio alginolyticus, contributes to virulence in fish and is a target for vaccine development: FISH & SHELLFISH IMMUNOLOGYZhou, Zejun Pang, Huanying Ding, Yu Cai, Jia Huang, Yucong Jian, Jichang Wu, Zaohe 出版年：2013; Type III secretion system (T3SS) in Vibrio alginolyticus is essential for its pathogenesis. VscO's homologous proteins FliJ, InvI and YscO have been suggested to be putative chaperone escorts although its function in V. ...

Protection against Vibrio alginolyticus in pearl gentian grouper (female Epinephelus fuscoguttatus x male Epinephelus lanceolatu) immunized with an acfA-deletion live attenuated vaccine: FISH & SHELLFISH IMMUNOLOGYChen, Yanyan Cai, Shuanghu Jian, Jichang 出版年：2019; Vibrio alginolyticus is well-known as an opportunistic Grain-negative pathogen, which endangers the development of global aquaculture as well as human health. In this study, a Delta acfA mutant strain and complementation...

溶藻弧菌疫苗对凡纳滨对虾免疫功能的影响: 《湛江海洋大学学报》曹剑香简纪常吴灶和出版年：2004; 应用溶藻弧菌疫苗饲喂凡纳滨对虾,测定了弧菌疫苗对凡纳滨对虾免疫指标的影响以及疫苗的免疫保护作用。结果发现,投喂弧菌疫苗后,溶菌活力在12～20d内迅速增强,在20d时活力达到最高,VF1组高于VF2和VF3组...; 关键词：凡纳滨对虾免疫指标免疫保护率影响因素溶藻弧菌疫苗 被引量：27

复方中草药对吉富罗非鱼生长及肠道菌群的影响: 《广东海洋大学学报》汤菊芬吴灶和简纪常鲁义善王蓓出版年：2009; 将A、B、C三种复方中草药分别按质量分数1.5%的比例添加到罗非鱼商品饲料中,喂养初始体重约16.58±0.48g的吉富罗非罗28d,通过测定罗非鱼的增重率、饲料系数、肠道菌群等指标,研究三种复方中草药制剂对罗非鱼生长性...; 关键词：中草药吉富罗非鱼生长肠道菌群 被引量：26

Traditional Chinese Medicine Enhances Growth, Immune Response, and Resistance to Streptococcus agalactiae in Nile Tilapia: JOURNAL OF AQUATIC ANIMAL HEALTHAbarike, Emmanuel Delwin Jian, Jichang Tang, Jufen Cai, Jia Yu, Huang Chen, Lihua 出版年：2019; Herbal supplements are suitable for improving fish health and combating diseases in fish culture. However, the mechanism of action of many herbal mixtures remains unclear. This study was conducted to evaluate the effects...

Identification and characterization of tumor necrosis factor receptor (TNFR)-associated factor 3 from humphead snapper, Lutjanus sanguineus: FISH & SHELLFISH IMMUNOLOGYCai, Jia Xia, Hongli Huang, Yucong Tang, Jufen Jian, Jichang Wu, Zaohe Lu, Yishan 出版年：2015; Tumor necrosis factor receptor (TNFR)-associated factor 3(TRAF3) is a key regulator in TNFR and Toll-like receptor (TLRs)/RIG-I-like receptors (RLRs) signal pathway. Here, a TRAF3 gene (Ls-TRAF3, GenBank Accession No: Kj...

虾类体液免疫研究进展: 《湛江海洋大学学报》曹剑香简纪常吴灶和出版年：2006; 关键词：对虾体液免疫研究进展 被引量：24

Short term starvation and re-feeding in Nile tilapia (Oreochromis niloticus, Linnaeus 1758): Growth measurements, and immune responses: AQUACULTURE REPORTSSakyi, Michael Essien Cai, Jia Tang, Jufen Xia, Liqun Li, Pengfei Abarike, Emmanuel Delwin Kuebutornye, Felix Kofi Agbeko Jian, Jichang 出版年：2020; The effects of short term starvation and re-feeding to satiation on compensatory growth performance, haematological parameters, biochemical parameters, and immune responses were investigated in Oreochromis niloticus of a...

Integrated analysis neurimmiRs of tilapia (Oreochromis niloticus) involved in immune response to Streptococcus agalactiae, a pathogen causing meningoencephalitis in teleosts: FISH & SHELLFISH IMMUNOLOGYWang, Bei Gan, Zhen Wang, Zhongliang Yu, Dapeng Lin, Ziwei Lu, Yishan Wu, Zaohe Jian, Jichang 出版年：2017; MicroRNAs (miRNAs) are a class of noncoding RNA molecules and play important roles in a wide spectrum of biological processes, including in immune response. Recent years have witnessed considerable amount of research int...

Influences of immunostimulants on phagocytes in cultured fish: a mini review: REVIEWS IN AQUACULTUREAbarike, Emmanuel D. Kuebutornye, Felix K. A. Jian, Jichang Tang, Jufen Lu, Yishan Cai, Jia 出版年：2019; Lower vertebrates like fish mostly depend on innate immunity as the first line of defence against invading pathogens. One of the defence mechanisms in innate immunity for fish is the use of phagocytic cells such as monoc...

Bacterial diversity in various coastal mariculture ponds in Southeast China and in diseased eels as revealed by culture and culture-independent molecular techniques: AQUACULTURE RESEARCHZeng, Yonghui Ma, Ying Wei, Chaoling Jiao, Nianzhi Tang, Kunxian Wu, Zaohe Jian, Jichang 出版年：2010; Mariculture ponds are widely distributed in Chinese coasts and have become a threat to the health of coastal ecosystems. In order to improve our understanding on the microbial composition in mariculture environments, we ...

饲料中添加沼泽生红冬孢酵母对凡纳滨对虾消化酶及肠道微生物的影响: 《水产科学》杨世平吴灶和简纪常出版年：2011; 在基础饲料中分别添加沼泽生红冬孢酵母干酵母和活酵母,在水温(26.2±1)℃、pH 7.4～8.0、盐度5条件下,进行为期6周的养殖试验。研究沼泽生红冬孢酵母对凡纳滨对虾肝胰腺消化酶和肠道微生物的影响。结果表明,饲料中添...; 关键词：凡纳滨对虾海洋红酵母沼泽生红冬孢酵母消化酶肠道微生物 被引量：21

中草药复合益生菌制剂对凡纳滨对虾生长、抗病力及水质的影响: 《广东海洋大学学报》汤菊芬黄瑜蔡佳鲁义善吴灶和简纪常出版年：2015; 将枯草芽孢杆菌、纳豆芽孢杆菌、地衣芽孢杆菌等比例混合,制成芽孢杆菌制剂;将芽孢杆菌制剂与粪肠球菌、嗜酸乳杆菌等比例混合制成复合益生菌制剂;将分别用3种芽孢杆菌发酵的中草药等比例混合制成中草药芽孢杆菌制剂;将分别用5种益生...; 关键词：凡纳滨对虾饲料添加剂益生菌制剂中草药复合制剂生长水质抗病力 被引量：20

红笛鲷头肾和脾脏显微结构的观察: 《台湾海峡》王鸿鹄李长玲曹伏君简纪常出版年：2006; 通过对红笛鲷头肾和脾脏显微结构的观察发现,头肾表面覆盖有一薄层纤维结缔组织性被膜,未见明显的小梁.实质主要由淋巴组织和血窦构成,可分为两个区,A区淋巴组织排列成索状,环血管呈放射状分布;B区的淋巴细胞则以形成弥散性分布淋...; 关键词：海洋生物显微结构红笛鲷头肾脾脏 被引量：20

Characterization of a tandem-repeat galectin-9 from Nile tilapia (Oreochromis niloticus) involved in the immune response against bacterial infection: FISH & SHELLFISH IMMUNOLOGYNiu, Jinzhong Huang, Yu Li, Yuan Wang, Zhiwen Tang, Jufen Wang, Bei Lu, Yishan Cai, Jia Jian, Jichang 出版年：2019; Galectin-9 is a < beta > -galactoside-binding lectin which could modulate a variety of biological functions including recognition, aggregation and clearance of pathogen. In this study, a galectin-9 homologue (OnGal-9) wa...

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